Named a “Best Book of the Year” by Kirkus Reviews
“Urgent and eye-opening, the book serves as a loud-and-clear alarm.”―The Boston Globe
Named an "Outstanding Academic Title" by Choice
From an MIT scientist, mounting evidence that the active ingredient in the world’s most commonly used weedkiller is contributing to skyrocketing rates of chronic disease.
Toxic Legacy: How the Weedkiller Glyphosate Is Destroying Our Health—Unveiling the Silent Threat to Metabolic and Neurological Health
Toxic Legacy by Dr. Stephanie Seneff exposes the far-reaching dangers of glyphosate, the active ingredient in Roundup, and its devastating impact on human health, gut microbiome balance, neurological function, and metabolic systems. This book is highly relevant to the Center for Integrative Neuroscience, as it aligns with our mission to uncover hidden environmental factors contributing to chronic illness, neurological disorders, and systemic healthcare failures.
How This Book Connects to Our Work
✔ Glyphosate’s Role in Metabolic & Neurological Dysfunction—Seneff reveals how glyphosate disrupts mitochondrial function, impairs energy metabolism, and interferes with neurotransmitter production, contributing to conditions such as autism, Alzheimer’s, depression, and chronic pain—all of which we address through integrative neuroscience and metabolic healing.
✔ The Gut-Brain Connection & Neuroinflammation—This book explores how glyphosate damages gut bacteria, increases intestinal permeability, and fuels chronic inflammation, aligning with our focus on restoring gut-brain health to improve cognitive and emotional well-being.
✔ The Medical System’s Failure to Recognize Environmental Toxins— Toxic Legacy exposes how corporate interests, regulatory agencies, and conventional medicine ignore or suppress evidence of environmental harm, mirroring our advocacy for transparency, whistleblowing, and reform in healthcare.
✔ Integrative Solutions for Detoxification & Healing—The book outlines ways to counteract glyphosate exposure, such as supporting metabolic function, enhancing detoxification pathways, and restoring gut integrity—all of which align with our evidence-based approaches to neuroprotection and regenerative health.
A Must-Read for Those Fighting Against Systemic Health Failures
For individuals who have witnessed or experienced the consequences of medical and environmental negligence, Toxic Legacy provides a critical examination of the hidden factors driving chronic disease and a roadmap for reclaiming health through integrative, metabolic, and neuroscience-informed strategies.
Glyphosate is the active ingredient in Roundup, the most commonly used weedkiller in the world. Over 300 million pounds of glyphosate-based herbicide are sprayed on farms―and food―every year.
Agrochemical companies claim that glyphosate is safe for humans, animals, and the environment. But emerging scientific research on glyphosate’s deadly disruption of the gut microbiome, its crippling effect on protein synthesis, and its impact on the body’s ability to use and transport sulfur—not to mention several landmark legal cases—tells a very different story.
In Toxic Legacy, senior research scientist Stephanie Seneff, PhD, delivers compelling evidence based on countless published, peer-reviewed studies—all in frank, illuminating, and always accessible language.
As Rachel Carson did with DDT in the 1960’s with Silent Spring, Seneff sounds the alarm on glyphosate, giving you guidance on simple changes you can make right now and essential information you need to protect your health, your family’s health, and the planet on which we all depend.
“A game-changer that we would be foolish to ignore.”―Kirkus Reviews (starred)
“Toxic Legacy will stand shoulder to shoulder with Rachel Carson’s Silent Spring. [This is] unquestionably, one of the most important books of our time.”―David Perlmutter, MD, #1 New York Times bestselling author of Grain Brain
“Dr. Seneff’s work will change the way we all think about food.”―Mark Hyman, MD, New York Times bestselling author